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The pros and cons of 12 popular sugar substitutes

Written by Robb Wolf (opens in a new tab)

Medically reviewed by Ecler Ercole Jaqua, MD, MBA, DABOM (opens in a new tab)

  1. Science →
  2. The pros and cons of 12 popular sugar substitutes

High sugar intakes have been linked to chronic inflammation, heart disease, type 2 diabetes, and a host of other modern diseases. The more sugar we eat, the fatter and sicker we getOpens in a new tab.

Fortunately, health-conscious people are growing increasingly aware of the harms of excess sugar consumption and they’re seeking out alternatives. 

But not all sugar substitutes are created equal. Many are simply other forms of sugar, not much different from the stuff in a diner. Thankfully however, there are a few healthy options available to choose from that we’ll cover today. 

One important thing to keep in mind: repeated exposure to sweet flavors calibrateOpens in a new tab our taste buds to prefer sweetness. So while great alternatives to sugar do exist, our best bet is to use them sparingly and put sweet flavors in their place as a mere afterthought.

That said, I hope this science-backed analysis of common sugar substitutes comes in handy! 

Spoiler alert: my preference is stevia. It provides the sweet taste of sugar without the health risks, and it has some potential health benefits. But in this article, I’ll cover many more high-carb, low-carb, and artificial sweeteners, supporting my claims with published evidence along the way. 

Let’s get started.

Higher-carb sugar substitutes

Many sugar substitutes aren’t actually alternatives to sugar. They’re just sugar masquerading under a different name. 

Sure, they might contain more antioxidants, vitamins, and minerals. But when you get down to business, they’re digested and metabolized in the same way as table sugar.

#1: High fructose corn syrup (HFCS)

High fructose corn syrup is a type of refined sugar used to sweeten foods and beverages. This corn-derived sweetener is the main source of added sugar in the American diet. Just like sucrose (table sugar), HFCS is a blend of glucose and fructose. The main difference is that high-fructose corn syrup is a bit higher in fructose. Who’d have thought?

Fructose seems to be the most problematic form of sugar. Animal evidenceOpens in a new tab suggests HFCS may drive cancer growth. And that’s just the tip of the fructose iceberg.

When you ingest fructose, it travels straight to the liver to be converted into fat. Our ancestors who developed this fructose-to-fat mutation tended to fare better compared to those who did not. They needed to bolster their fat stores in preparation for periods of caloric deprivation — much like a bear preparing to hibernate through the winter. 

In today’s environment of sugar abundance however, this mutation is simply fueling the obesity epidemic.

If you want to take a deep dive into this stuff, I recommend reading Fat ChanceOpens in a new tab by Dr. Robert Lustig. It’s an eye-opening exposition of the dangers of fructose in the modern diet.

Verdict: HFCS is bad news. It’s a liquid form of refined sugar that’s making us fat and sick.

#2: Agave syrup

Made from the agave plant, agave syrup is often marketed as a healthy sugar substitute. The reality: depending on processing, it can contain about 80% fructose Opens in a new tab— potentially higher than both sucroseOpens in a new tab (~50%) and HFCSOpens in a new tab (~55%). The high fructose content matters particularly when consumed in isolation from fiber,Opens in a new tab which is present in the original agave plant but removed during processing.

Verdict: Substituting table sugar with agave syrup is like substituting a Danish pastry for a donut. It’s not any better, and it might even be worse.

#3: Honey

Made by bees, honey is a preferred sweetener of many who adhere to a Carnivore diet. It’s the only animal-based sweetener on this list and it has some cool properties, especially if it’s raw.

Compounds in raw honey like bee pollen, royal jelly, and propolis may improveOpens in a new tab immune function and reduce allergies, but more rigorous research is needed to solidify these claims. Honey also contains flavonoids with potent antioxidant effects. IngestingOpens in a new tab these flavonoids may help with wound healing, blood glucose regulation, immune healthOpens in a new tab, and more.

However, much like sucrose and HFCS, honey is mostly fructose and glucose. It’s sugar.

Verdict: Honey may have health benefits, but it’s still a sugar bomb. Use wisely such as before or after a workout.

#4: Molasses

Molasses is a thick, brown syrup made by boiling down sugar cane. It’s simply a reduced form of sugar.

Anything to like about molasses? Actually, yes. It’s high in iron, potassium, manganese, magnesium, and copper — all of which are essential minerals for heartOpens in a new tab, bone, and immune health. Manganese, for instance, helpsOpens in a new tab your blood vessels stay dilated to support healthy blood pressure.

Verdict: Molasses contains more minerals than sucrose, but if you’re avoiding sugar, it’s not a good choice.

#5: Coconut sugar

Here are the pros and cons of coconut sugarOpens in a new tab, a type of carbohydrate made from coconut sap.

Pros:

  • Contains antioxidants, zinc, iron, calcium, and potassium
  • Has a lower glycemic index than sucrose (in other words, it raises blood sugar more slowly)
  • Contains inulin, a prebiotic fiber that can feed beneficial gut bacteria and improve digestion

Cons:

  • Equivalent in calories to sugar
  • Contains loads of fructose, the fat-forming sugar we covered earlier

Verdict: Coconut sugar is just sugar with a few extra nutrients.

#6: Maple syrup

Most people think of maple syrup as an essential topping for pancakes and waffles, not a vehicle for antioxidants and oligosaccharides — but maple syrup is high in both.

It’s reportedOpens in a new tab to have more antioxidant force than honey, while its oligosaccharides (a compound sugar molecule) may improve glucose regulation. When rodents were fedOpens in a new tab maple syrup along with sucrose, it curbed their blood sugar spike compared to sucrose alone. Despite these beneficial properties, maple syrup is still mostly sucrose.

Verdict: Maple syrup is healthier than table sugar, but it’s no health food.

#7: Yacon syrup

From the Yacon Plant native to South America comes yacon syrup — a thick, saccharin goo similar in taste and texture to molasses. Yacon is part sugar, part fructooligosaccharides (FOS).

What are FOS? They’re prebiotic carbohydrates that aren’t digested through normal routes, but instead by gut bacteria. Consuming FOS may have health benefits (such as increased satietyOpens in a new tab), but gas is a SUPER common side effect. Don’t give yacon syrup a test drive before a first date.

Yacon has about one-third the calories as sugar, so that’s a plus. But unless it’s used sparingly, it’s not compatible with a low-carb or keto dietOpens in a new tab.

Verdict: Yacon syrup is lower in calories than sugar, but it may give you gas.

A Word On Artificial Sweeteners

Artificial sweeteners like sucralose, aspartame, and saccharine appear to be generally safe for human consumption. (The aspartame cancer scare is way overblownOpens in a new tab.) And since they don’t contain calories or carbs, they don’t derail a ketogenic diet.

Still, I’m not a big fan of these lab-synthesized sweeteners. In one observational studyOpens in a new tab, people consuming diet soda daily had a 67% higher risk of developing type 2 diabetes than non-consumers. This doesn’t prove causation, but I’m also not about to ignore it outright.

There’s also evidenceOpens in a new tab that consuming artificial sweeteners during pregnancy negatively impacts the baby’s body composition and augments their sweet tooth. So I don’t recommend them for pregnant or nursing women.

Recent research has raised additional concerns about artificial sweeteners:

  • A 2022 research studyOpens in a new tab concluded that artificial sweeteners can alter gut microbiome composition (the mix of bacteria in your gut) and may affect glucose tolerance (how the body handles blood sugar) in some individuals.
  • The World Health Organization released 2023 guidelinesOpens in a new tab discouraging the use of non-sugar sweeteners for weight control, citing lack of long-term benefit and potential risks.
  • Different artificial sweeteners appear to have different effectsOpens in a new tab in the body, so we shouldn’t assume they’re all alike.

That said, major health agencies including the Food and Drug Administration (FDA) and European Food Safety Authority (EFSA) continue to affirm their safety within acceptable daily intake levels.

Verdict: I generally avoid artificial sweeteners. I don’t think they’re poison, but there are certainly better options out there.

Low-carb sugar substitutes

Now for the good stuff: the natural sugar alternatives that sweeten without the calories and blood sugar spikes of sugar. Individual responses to these sweeteners can vary, so it's worth experimenting to find what works best for your body and taste preferences.

#8: Stevia

Extracted from the leaves of the stevia rebaudiana plant, stevia extract doesn’t raise blood sugar, has powerful antioxidant properties, and it’s 200–300 times sweeter than sugar.

All of stevia’s characteristics — including its sweetness — are driven by molecules called glycosidesOpens in a new tab. The most active glycosides are:

  • Stevioside
  • Rebaudioside A
  • Rebaudioside C
  • Dulcoside

I’ll also note that stevia has been used for hundreds of years to treat diabetes in South America. Today it’s being studiedOpens in a new tab for similar purposes.

Verdict: SteviaOpens in a new tab is my preferred sugar substitute, particularly for anyone who eats a low-carb or ketogenic diet. That’s why we use it in LMNTOpens in a new tab.

#9: Monk fruit

Similar to stevia, monk fruit extract is 250 times sweeter than sugar, contains zero calories, and is powered by antioxidant compounds called mogrosides.

Monk fruit has been deemed safe by the FDA, but stevia has a bit more data behind it. Both are good low-carb sweeteners.

Verdict: Monk fruit is a great alternative sweeter to sugar.

#10: Allulose

Last but not least, we come to allulose. Of all the low-carb sweeteners, allulose is probably the most similar to sugar in taste and texture. It even browns.

Found in figs and jackfruit, allulose is technically a sugar, but it’s not metabolized like sugar. Most of it gets excreted through urine, which is why it’s non-caloric. When taken with carbs, allulose has been shownOpens in a new tab to reduce the resulting blood sugar spike by an average of 10%. And one small study also foundOpens in a new tab that allulose increased fat burning.

Allulose is relatively new to the commercial market, receiving FDA GRAS (Generally Recognized As Safe) status in 2012Opens in a new tab. While initial research is promising, long-term human studies are still limited. Most people tolerate it well, though some report mild digestive effectsOpens in a new tab at higher doses.

Verdict: If you’re looking to replace sugar (in recipes or otherwise), using allulose is a decent way to accomplish that goal.

#11: Erythritol

These last two are sugar alcohols — which, by the way, are neither sugar nor alcohol. They’re carbs that aren’t digested or metabolized, similar to fiber. Sugar alcohols’ primary downside is the potential to upset your stomach. Nausea, laxation, gas, and bloating are possible, so keep an ear out for your grumbling stomach.

ErythritolOpens in a new tab is a sugar alcohol produced by yeast fermentation. It’s about 70% as sweet as sugar, has a cooling aftertaste, and features a glycemic index of zero. When you consume erythritol, about 90% is excreted intact through urine. That’s why it doesn’t affect blood sugar or insulin levels, making it keto-approved. It also has antioxidant properties and interestingly, it’s been shownOpens in a new tab to improve blood vessel function in a small group of type 2 diabetics. That said, recent literature indicates that erythritol may not be heart healthy. I wrote a full article dissecting that study's pros and consOpens in a new tab if you're curious.

Verdict: It's probably best to consume less erythritol while we wait for more data.

#12: Xylitol

Like erythritol, xylitol is a sugar alcohol. As for cons, it has a glycemic index of 13 and folks tend to report more digestive distress with xylitol than erythritol. But on the positive end, xylitol hasn't been linked to cardiovascular disease and it's well-documentedOpens in a new tab to improve oral health. Hence why it's a popular choice of sweetener in gum.

Verdict: If your gut tolerates xylitol well, it's a healthier option than sugar.

Sugar Substitute Recommendations by Goal

Best for Keto/Low-Carb

  • Stevia
  • Monk Fruit
  • Allulose

All three are zero-carb, zero-glycemic-impact sweeteners that won't interfere with ketosis.

Best for Baking

  • Stevia
  • Monk Fruit
  • Allulose

Allulose is the most similar to sugar in taste and texture. It even browns like sugar, making it ideal for baked goods.

Safest Track Record 

  • Stevia 

Stevia has been used for hundreds of years to treat diabetes in South America, giving it the longest history of human consumption among modern low-carb sweeteners.

Most Versatile

  • Stevia 

Stevia remains stable in both hot and cold applications and works well across beverages, recipes, and food products, which is why we use it in LMNT.

Final Thoughts On Sugar Substitutes

If you're cutting back on sugar, you're already ahead of the game. 

But a lot of products marketed as "sugar substitutes" are just sugar with a different name slapped on the label: Agave, coconut sugar, honey — they're all going to spike your blood sugar just like table sugar does.

When you actually need to sweeten something, stick with stevia, monk fruit, or allulose. They won't mess with your blood sugar, and they've got decent evidence behind them. 

That said, the best strategy is to gradually dial back your taste for sweet stuff altogether.

So use these alternatives when you need them, but don't use them as a license to keep everything in your life tasting like candy. Your taste buds will adapt, and eventually, you might find that a lot of the sweet stuff you thought you needed doesn't even taste that good anymore.


Updated November 2025

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