<p><span style="font-weight: 400">If you’ve been watching the news in recent months, you might have seen that the FDA launched </span><a href="https://www.fda.gov/regulatory-information/search-fda-guidance-documents/guidance-industry-voluntary-sodium-reduction-goals" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">another attack</span></a><span style="font-weight: 400"> in their perpetual war on salt. </span><span style="font-weight: 400">If the US government had its way, we’d all consume fewer than 2.3 grams of sodium per day. According to the FDA, a low-salt diet would reduce our collective risk of heart disease and save hundreds of thousands of lives.</span></p><p><span style="font-weight: 400">If that were accurate, then all aboard! Sounds great to me. But as you’ll see, this recommendation is far off the mark. When you really drill into these claims, you come back empty-handed. You find <a href="https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.111.201293?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed" target="_blank" rel="noopener noreferrer">papers</a> that cherry-pick epidemiology and make absurd assumptions to defend salt restriction.</span></p><p>On the other hand, we have <em>massive</em> population studies (e.g., <a href="https://pubmed.ncbi.nlm.nih.gov/3416162/" target="_blank" rel="noopener noreferrer">The Intersalt Study</a>) that have already settled this debate. Across 48 global populations, dietary salt intake didn’t predict the prevalence of high blood pressure. The highest salt population actually had a lower median blood pressure than the lowest salt population.</p><p><span style="font-weight: 400">I’ll concede that sedentary people who eat an ultra-processed diet <a href="https://pubmed.ncbi.nlm.nih.gov/19955402/" target="_blank" rel="noopener noreferrer">tend</a> to consume more salt on average, and that they <a href="https://pubmed.ncbi.nlm.nih.gov/32792031/" target="_blank" rel="noopener noreferrer">tend</a> to suffer worse health outcomes too. But against the backdrop of the population studies I just referenced, it’s pretty clear that salt isn’t the culprit influencing these poor outcomes—it’s the ultra-processed diet combined with a sedentary lifestyle.</span></p><p><span style="font-weight: 400">And why did the FDA neglect even once to mention the dangers of sugar in its guidance to the food industry? <a href="https://drinklmnt.com/blogs/health/how-sugar-is-making-us-sick" target="_blank" rel="noopener noreferrer">A high-sugar diet</a> (combined with inactivity) is a recipe for obesity and diabetes. The more people overeat, the more weight they gain, the higher their risk for metabolic disaster and heart disease. The science is <a href="https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC2862465/" target="_blank" rel="noopener noreferrer">clear</a> on this point, and it’s no secret that sugar is both calorically dense and hyperpalatable.</span></p><p><span style="font-weight: 400">So why is salt blamed for the epidemic of diet-related illness instead of sugar? Perhaps it’s because the sugar industry <a href="https://www.nytimes.com/interactive/2019/08/14/magazine/sugar-slave-trade-slavery.html" target="_blank" rel="noopener noreferrer">receives</a> billions of dollars per year in government subsidies. Money talks. Well, science and data talk too. And I plan to amplify their voice loud, clear, and salty today. Let’s get into </span><span style="font-weight: 400">the FDA’s (mis)guidance on sodium</span><span style="font-weight: 400">.</span></p><h2><b>The New FDA Guidance on Salt</b></h2><p><span style="font-weight: 400">The </span><a href="https://www.fda.gov/food/food-additives-petitions/sodium-reduction" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">new guidance on salt</span></a><span style="font-weight: 400"> is mostly the same as the old guidance on salt. The FDA still wants adults to consume under 2.3 grams of sodium per day.</span></p><p><span style="font-weight: 400">The “new” part is that food manufacturers and restaurants are being asked directly to significantly reduce sodium in the food supply. To be clear, this isn’t a requirement, but a strong suggestion.</span></p><p><span style="font-weight: 400">According to the FDA, the average American consumes 3.4 grams of sodium per day. The goal of these measures is to reduce it to 3 grams per day.</span></p><p><span style="font-weight: 400">Assuming food companies comply, the measures might succeed in reducing sodium intake. After all, the bulk of sodium in the American diet </span><i><span style="font-weight: 400">does </span></i><span style="font-weight: 400">come from </span><a href="https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.116.024446" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">outside foods</span></a><span style="font-weight: 400">, not the salt shaker at home.</span></p><p><span style="font-weight: 400">The FDA’s case, by the way, rests on “strong scientific evidence” that salt restriction reduces blood pressure. The reduction in blood pressure, in turn, is supposed to lower our collective risk of heart attack and stroke. If their </span><a href="https://www.fda.gov/regulatory-information/search-fda-guidance-documents/guidance-industry-voluntary-sodium-reduction-goals"><span style="font-weight: 400">report</span></a><span style="font-weight: 400"> is to be believed, sodium restriction in line with government recommendations will save up to 500,000 lives over ten years.</span></p><p><span style="font-weight: 400">But when you double click on these claims, you find vigorous conjecture, unfounded assumptions, and aggressive extrapolation. The 500,000 lives figure, for instance, is partly based on </span><a href="https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.111.201293?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">data</span></a><span style="font-weight: 400"> from anti-hypertensive drug trials. The assumption—and I’m not making this up—is that the success of blood pressure meds in clinical trials should serve as a proxy for the possible success of sodium reduction.</span></p><p><i><span style="font-weight: 400">Hm, we know that hypertensive drugs work. Let’s attach the low sodium cart to that horse and then claim it will save lives. </span></i><span style="font-weight: 400">That appears to have been the thought process.</span></p><p><span style="font-weight: 400">The remainder of the FDA’s evidence was carefully chosen to make their case. Hypertensive people, for instance, are more likely to be </span><a href="https://drinklmnt.com/blogs/health/salt-sensitivity" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">salt-sensitive</span></a><span style="font-weight: 400"> due to insulin resistance, </span><a href="https://pubmed.ncbi.nlm.nih.gov/32862203/" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">kidney issues</span></a><span style="font-weight: 400">, and other factors—so those were the populations they looked at.</span></p><p><span style="font-weight: 400">We’ll return to salt and blood pressure throughout this article. Right now, though, let’s reflect on how this confusion began.</span></p><h2><b>How The War on Salt Began</b></h2><p><span style="font-weight: 400">The US Dietary Guidelines were first </span><a href="https://fns-prod.azureedge.net/sites/default/files/dietary_guidelines_for_americans/1980thin.pdf" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">published</span></a><span style="font-weight: 400"> in 1980. There were a few good recommendations (like encouraging sugar avoidance), but the document also admonished us to avoid fat, saturated fat, cholesterol, and—yes—salt.</span></p><p><span style="font-weight: 400">The anti-salt edict was based mostly on research from the 1960s. Back then, a scientist named Lewis Dahl </span><a href="https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC2118645/" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">found</span></a><span style="font-weight: 400"> that giving rats about 150 times the human-equivalent daily dose of sodium gave them high blood pressure. His findings made sense. A huge hit of sodium </span><i><span style="font-weight: 400">will</span></i><span style="font-weight: 400"> raise blood volume and blood pressure, but it says nothing about </span><a href="https://science.drinklmnt.com/electrolytes/does-salt-help-with-hydration/" target="_blank" rel="noopener"><span style="font-weight: 400">normal human intakes of salt</span></a><span style="font-weight: 400">.</span></p><p><span style="font-weight: 400">Along with Dahl’s data, the FDA also found a few observational data points to support the “salt is bad for blood pressure” hypothesis.[<a href="https://jamanetwork.com/journals/jama/article-abstract/1695838" target="_blank" rel="noopener noreferrer">*</a>][<a href="https://effectivehealthcare.ahrq.gov/products/sodium-potassium/final-report-2018" target="_blank" rel="noopener noreferrer">*</a>][<a href="https://pubmed.ncbi.nlm.nih.gov/2767757/" target="_blank" rel="noopener noreferrer">*</a>]</span></p><p><span style="font-weight: 400">This paper-thin case has been used for decades to justify low-sodium recommendations. Today they recommend capping daily sodium intake at 2.3 grams—an intake likely to cause </span><a href="https://drinklmnt.com/blogs/health/electrolyte-imbalance-or-deficiency" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">sodium deficiency</span></a><span style="font-weight: 400"> in most people, particularly athletes.</span></p><h2><b>Salt and Blood Pressure</b></h2><p><span style="font-weight: 400">High blood pressure is a </span><a href="https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6477925/" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">primary risk factor</span></a><span style="font-weight: 400"> for heart attack, stroke, dementia, and other poor health outcomes related to the vascular and cerebrovascular systems. We want to avoid it whenever possible.</span></p><p><span style="font-weight: 400">The FDA says lowering salt intake will accomplish this goal. Their entire argument hinges on it. I already talked about the FDA’s supporting </span><a href="https://www.fda.gov/regulatory-information/search-fda-guidance-documents/guidance-industry-voluntary-sodium-reduction-goals" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">evidence</span></a><span style="font-weight: 400">. It’s based mostly on epidemiology and conjecture.</span></p><p><span style="font-weight: 400">When you look at the whole picture, the narrative changes. Consider the following:</span></p><ul><li style="font-weight: 400"><a href="https://pubmed.ncbi.nlm.nih.gov/3416162/" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">The Intersalt Study</span></a><span style="font-weight: 400"> looked at over 10,000 people across 48 global populations and found NO correlation between salt intake and the prevalence of hypertension. If salty diets raised blood pressure, it would show up here.</span></li><li style="font-weight: 400"><a href="https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.31.1_supplement.446.6" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">The Framingham Offspring Study</span></a><span style="font-weight: 400"> found that sodium intakes under 2.5 grams per day were linked to HIGHER blood pressures than sodium intakes above 2.5 grams per day in 2,632 people without</span> <span style="font-weight: 400">hypertension. In other words, the low sodium group had higher blood pressure.</span></li><li style="font-weight: 400"><span style="font-weight: 400">A 2020 </span><a href="https://pubmed.ncbi.nlm.nih.gov/33314019/" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">systematic review</span></a><span style="font-weight: 400"> from the Cochrane Collaboration found that sodium restriction was linked to less than half a point reduction (on average) in blood pressure in normotensive white people—with “weak evidence” that black and Asian people might see better effects. The negative side effects of sodium restriction were “more consistent than the effect on BP.”</span></li></ul><p><span style="font-weight: 400">I’ll talk more about the health risks of low sodium diets soon. Let’s review the data on sodium and heart health now.</span></p><h2><b>Salt and Heart Health</b></h2><p><span style="font-weight: 400">If low sodium diets were good for your heart, you would see it in the data. But I haven’t seen it, and I’ve spent so much time with the data that my family hasn’t seen me since last February when I briefly emerged to grab a cup of coffee and a handful of macadamia nuts.</span></p><p><span style="font-weight: 400">Just kidding, but you get the idea. My point is: the literature on sodium is extensive and mostly unsupportive of the FDA’s views. Some examples will help illustrate.</span></p><p><span style="font-weight: 400">In a 2011 </span><a href="https://pubmed.ncbi.nlm.nih.gov/22110105/" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">study</span></a><span style="font-weight: 400"> published in the Journal of the American Medical Association (JAMA), researchers looked at salt intakes and hard heart disease outcomes (heart attack, stroke, death) in 28,800 high-risk heart disease patients. They found that the lowest risk for bad outcomes—the “sweet spot,” if you will—was between 4 to 6 grams of sodium per day. People restricting sodium had a 19% higher risk of cardiovascular death than those in the sweet spot.</span></p><p><span style="font-weight: 400">Other research tells a similar story. For instance, a </span><a href="https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2712563?guestAccessKey=8d6f8001-a1f8-4372-b8b9-a7d935d5d7a4&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jamainternalmedicine&utm_content=olf&utm_term=110518" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">2018 review</span></a><span style="font-weight: 400"> (also in JAMA) found little evidence that reducing salt intake helps with heart failure.</span></p><p><span style="font-weight: 400">This doesn’t mean we should consume unlimited sodium. Too much sodium isn’t optimal either. But most people need at least 4–6 grams of sodium per day. (More if they’re </span><a href="https://drinklmnt.com/blogs/health/how-to-hydrate-for-endurance-sports" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">active</span></a><span style="font-weight: 400"> or eat a ketogenic diet.) So what happens when you’re light on sodium?</span></p><h2><b>The Problem With Low Salt Diets</b></h2><p><span style="font-weight: 400">When you don’t get enough sodium, your body goes into </span><a href="https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3951800/" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">sodium retention mode</span></a><span style="font-weight: 400">. You release sodium retention hormones (aldosterone, renin, angiotensin, and norepinephrine) that make your kidneys retain sodium.</span></p><p><span style="font-weight: 400">Unfortunately, these hormones also raise blood pressure. Why do you think sodium </span><i><span style="font-weight: 400">restriction</span></i><span style="font-weight: 400"> is </span><a href="https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.31.1_supplement.446.6" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">linked</span></a><span style="font-weight: 400"> to elevated blood pressure in healthy people? It’s those pesky hormones. This seems counterintuitive, doesn’t it? Welcome to complex systems!</span></p><p><a href="https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6140170/" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">Osteoporosis</span></a><span style="font-weight: 400"> is another consequence of a low salt diet. Your bones serve as a sodium reservoir—and when you limit salt intake, your body pillages that reservoir of not just sodium, but also calcium and magnesium.</span></p><p><span style="font-weight: 400">Then there are the outward </span><a href="https://science.drinklmnt.com/electrolytes/symptoms-of-low-sodium-and-how-to-treat-hyponatremia/" target="_blank" rel="noopener"><span style="font-weight: 400">low sodium symptoms</span></a><span style="font-weight: 400">. I’m talking about the low energy, headaches, </span><a href="https://drinklmnt.com/blogs/health/what-causes-muscle-cramps#:~:text=Low%20sodium%20is%20probably%20the,cramps%20are%20likely%20to%20occur." target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">muscle cramps</span></a><span style="font-weight: 400">, fatigue, weakness, insomnia, and malaise so common in folks on whole foods diets who do not consume adequate sodium.</span></p><p><span style="font-weight: 400">You may have heard of <a href="https://drinklmnt.com/blogs/health/what-causes-keto-flu-and-6-keto-flu-remedies" target="_blank" rel="noopener">keto flu</a>—it’s characterized by a lot of the symptoms I listed above. Yeah, that’s typically just a sodium issue.</span></p><p><span style="font-weight: 400">I’m not saying </span><a href="https://drinklmnt.com/blogs/health/is-sodium-good-or-bad-for-you" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">sodium</span></a><span style="font-weight: 400"> is a cure-all. It’s not. But most people—especially active, health-conscious folks—need more salt to feel and perform their best.</span></p><h2><b>The Truth About the Salty Science</b></h2><p><span style="font-weight: 400">The FDA paints salt as a villain but, be it intentionally or neglectfully, they’re not representing the best scientific literature we have very well.</span></p><p><span style="font-weight: 400">The science says that salt restriction is ineffective for lowering blood pressure and leads to side effects you don’t want. It also says the </span><a href="https://pubmed.ncbi.nlm.nih.gov/22110105/" target="_blank" rel="noopener noreferrer"><span style="font-weight: 400">sweet spot</span></a><span style="font-weight: 400"> for sodium intake is at least double what the government recommends.</span></p><p><span style="font-weight: 400">The FDA’s war on salt is costing us. Not only does demonizing salt divert our attention from finding real solutions to our health crisis (e.g. studying the consumption of hyperpalatable foods), but it also fosters unhealthy fear of an essential mineral. Please share this article to someone who needs to see it. Help me push back so we can help the world stay healthy, salty, and sane.</span></p>