Toxicology in context

Heavy metals edition

Watch this 12-minute video and you’ll understand heavy metals better than 99% of your friends.

The internet is drowning in misinformation masked as health advice.

Many publishers, brands, and creators start with a genuine desire to help you navigate the already confusing health landscape — but then end up falling into the fabricated fear-for-profit game. It gets the clicks… but reach and rigor are different skills, and the algorithm only rewards one of them.

You’ve probably seen content that tells you:

The food you eat is toxic!
The products you buy are poisoning you!

You’re someone looking out for your health — not someone to get conned over clickbait. And anyone trying to make reasonable health decisions deserves credible information that helps them decipher what’s worthy of their time and concern… and what’s not.

Introducing: Toxicology in Context — a content series to help you understand these issues (starting with heavy metals, with more editions to come). There’s no one path to health — make your own (informed) call.

Part 01

A brief history of heavy metals

A brief history of heavy metals

Your blood carries far less lead than it did in 1980. So why are we more afraid of carrots than our grandparents were of lead paint?

From lead paint chips to trace parts per billion (ppb) in cookies, exposure to heavy metals has decreased in recent decades. The real story arc here isn’t rising danger — it’s unprecedented progress.

From 1976 to 1980, the average American’s blood contained about 12.8 micrograms of lead per deciliterOpens in a new tab (µg/dL), roughly three and a half times today’s reference value of 3.5 µg/dL.Opens in a new tab Thanks to decades of regulation, median blood lead levels in young children have dropped 95% in a generationOpens in a new tab. Yet we worry more about trace metals in everyday foods than our grandparents did about lead paint.

Science keeps improving its ability to detect trace substances, but public understanding hasn’t kept pace.

Let’s break down how heavy metal testing has evolved — and what those measurements actually mean — so you can make sense of the scope when seeing toxicology reports (like the panic over protein powdersOpens in a new tab not too long ago) make the news.

Heavy Metal Exposure in the Past vs. Today

Lead, mercury, arsenic, and cadmium are naturally occurring elements — part of the Earth’s crust, air, and water. But human use amplified our exposure:

Practices like these caused environmental and health disasters, including Minamata BayOpens in a new tab in Japan (mercury poisoning), “Itai-itai” diseaseOpens in a new tab in Japan (cadmium poisoning), arsenic-tainted wellsOpens in a new tab in Bangladesh that affected millions, and perhaps most well-known, the Flint, Michigan water crisisOpens in a new tab that exposed tens of thousands of residents to elevated lead levels in drinking water.

By 1980, we finally had national-scale data to quantify the lead crisis. The Second National Health and Nutrition Examination Survey measuredOpens in a new tab an average U.S. blood-lead level of 12.8 µg/dL with more than one in five young childrenOpens in a new tab exceeding 20 µg/dL — confirming how widespread the exposure really was across the country.

When Heavy Metal Regulation Started Working

U.S. population blood lead levels

Blood lead levels are down ~94% since 1976

Federal regulation dramatically reduced lead exposure by removing the biggest sources — leaded gasoline, lead-based paint, and lead-soldered food cans.

04812CDC blood lead reference value · 3.5 µg/dL 12.81976–802.81988–912.31991–941.661999–000.752017–18 µg/dL

From the late 1960s into the 1990s, researchers such as Herbert Needleman, M.D.Opens in a new tab observed an association between elevated lead levels and impaired cognitive and behavioral development. It added to a growing awareness of lead’s broader health hazardsOpens in a new tab that drove decades of regulation.

These findings reframed lead as a developmental toxin rather than a benign industrial material, which spurred a wave of regulatory action:

The takeaway: Targeted, evidence-based regulation works.

Now, population blood lead levels are monitored through the ongoing NHANES survey program.

NHANES recruits new samples of people across the U.S. Each year, thousands of participants complete interviews, physical examinations, and laboratory testing, including blood lead measurement for eligible participants. Complex sampling and statistical weighting are used to produce nationally representative estimates.

That means we’re not guessing whether Americans’ lead exposure has risen or fallen based only on environmental measurements or food testing. We can look at how much lead is showing up in people’s blood and track changes over decades.

Why Testing Shows More “Problems” Now: Modern Detection and Misunderstanding

So why does it feel like heavy metals are everywhere? Because modern testing can see almost everything.

Today’s instruments can detect elements in parts per billion — with one part per billion being the equivalent of a single drop in an Olympic-sized pool. That precision is a major win for safety monitoring but also a recipe for misunderstanding.

It started in the 1970s when toxicologist Dr. Bruce Ames developed a test so sensitive it could detect mutagens in everyday foods like coffeeOpens in a new tab. People misinterpreted this to believe that coffee causes cancer. Ames had to clarifyOpens in a new tab that detection did not equal danger and that science’s ability to measure something doesn’t automatically make it meaningful.

Fast forward to today’s information age, and misinformation spreads faster than facts. A single headline, TikTok clip, or infographic can ignite national (and even international) panic before experts have time to explain what the data mean. Detection technology has outpaced science literacy, and fear often fills the gap.

That’s why trace findings often sound alarming — because the numbers are missing context. For example, a two-cookie serving with 1 microgram (µg) of leadOpens in a new tab may seem worrisome until you learn that a medium carrot contains 1.7 mcgOpens in a new tab and a medium potato has 2.4 mcgOpens in a new tab, simply because plants naturally absorb minerals from soil. To put that in perspective, a microgram is about the size of one bacterial cell — invisible to the naked eye.

The presence of heavy metals in parts per billion doesn’t imply harm. Toxicity depends on dose, exposure, bioavailability, and your body’s own ability to metabolize and excrete substances. It also depends on a person’s individual susceptibility — children and pregnant women are particularly vulnerable.

When Heavy Metal Safety Standards Don’t Reflect Science

Modern food and environmental safety programs should continue refining how we monitor contaminants, but not all standards are created equal.

Take California’s Proposition 65Opens in a new tab: It was originally designed to protect drinking water from industrial contamination, then was later applied to foods and packaged goods without accounting for bioavailability — how much of a substance your body absorbs.

The result? Proposition 65 requires the “no observable effect level” to be divided by 1,000Opens in a new tab in order to provide an ample margin of safety. The limit is so strict it flags even trace amounts naturally found in natural foods.

Prop 65 isn’t recognized by the FDA or EPA as a federal safety standard, and while its intent may be protective, its limits often don’t reflect toxicological reality.

In truth, if you eat whole foods like vegetables, grains, or meats, you’re already consuming more than a microgram of lead a day — another reminder that detection isn’t danger.

Vegetable Organic (mcg/kg) Conventional (mcg/kg) Amount per standard serving of conventional
Tomato 5.0 7.7 ~1.1 mcg per 1 medium tomato
Lettuce 12.0 25.3 ~2.2 mcg per 1.5 cups of chopped lettuce
Onion 3.0 19.0 ~2.8 mcg per 1 medium onion
Carrot 7.2 22.4 ~1.8 mcg per 1 medium carrot
Potato 32.6 16.5 ~2.4 mcg per 1 medium potato

Source: Assessment of trace metals in five most-consumed vegetables in the US: Conventional vs. organicOpens in a new tab

Are We Safer From Heavy Metals Today?

There was a time when metal toxicity was a genuine public-health threat. Leaded gasoline, lead-based paint, and industrial discharge were not abstract risks; they were widespread, persistent exposures with real consequences.

We have largely won that battle. Those major sources have been dramatically reduced or eliminated in the United States, and the result is a generational drop in exposure to leadOpens in a new tab.

Today, what remains is largely trace amounts that have always existed in the natural world, and their continued detection is a sign of progress, not regression. Our bodies are not passive vessels, either; they’re equipped with robust systemsOpens in a new tab that process and clear many compounds safely, including trace heavy metals naturally found in foods, drinks, and household items. Of course, your body’s ability to eliminate heavy metals will vary based on the exact metal and your level of exposure.

We are, in many ways, safer than ever.

The real progress story isn’t hidden in trace detections, it’s in decades of data that prove science-backed regulations have drastically reduced real risk.

Key takeaway

You’re safer from heavy metals than your great-grandparents ever were.

NextPart 02 · Toxic metals vs. toxicology: Why dose matters

Part 02

Toxic metals vs. toxicology: Why dose matters

Toxic metals vs. toxicology: Why dose matters

A pear contains formaldehyde. Too much water can kill you. The poison was never the ingredient. It’s the dose.

It’s hard to open social media or check the news these days without seeing a scary health story or alarming meme about heavy metals in foods. The media landscape is awash in seemingly nonstop heavy metal fear-mongering.

Arsenic in Girl Scout cookiesOpens in a new tab. Lead in protein powdersOpens in a new tab. Lead and cadmium in chocolateOpens in a new tab.

These headlines tap into a primal fear: What if the food we’re eating is poisoning us?

But here’s what’s missing from that panic: the difference between detecting a substance and that substance being dangerous. Between “this food contains lead” and “this food will harm you” lies an entire science that most headlines miss.

A toxicant is any substance that can cause harm to living organisms at the right (or wrong) dose.

Toxicology is the science of understanding how those substances actually affect living organisms. It’s about dose, timing, route of exposure, and how our bodies process what we consume. It’s the difference between “this exists” and “this will hurt you.”

Heavy metals exist naturally in trace amounts everywhere — in soil, water, and air. That means they’re in our food. Not from contamination, but from the earth itself. Humans have been exposed to trace amounts of these substances for thousands of years.

What toxicology tells us is that the mere presence of heavy metals doesn’t make food unsafe. What matters is how much we consume and whether that amount actually causes harm.

Understanding this distinction is what separates rational food choices from fear-based ones.

Key takeaway

Social media is filled with fabricated fear.

The 5 Principles of Toxicology (and What They Mean For Your Food)

To understand the actual risks that heavy metals do — and don’t — pose in our diets, let’s examine the five key principles of toxicology:

  • The dose makes the poison.
  • The route of exposure matters.
  • Bioavailability is key.
  • Our bodies have natural detox systems.
  • Every body is different.

Why dose makes the poison

Perhaps no adage is more important to toxicology than “the dose makes the poison.”

It traces back to the 16th century physician ParacelsusOpens in a new tab, whose actual words were a bit more long-winded: “In all things there is a poison, and there is nothing without a poison. It depends only upon the dose whether a poison is poison or not.”

It helps to consider some specific examples: Formaldehyde is a chemical that, in large enough doses, can cause cancerOpens in a new tab. But a medium-large pear weighing 200 g contains nearly 8 to 12 mgOpens in a new tab of formaldehyde, and no dietitian would tell you to swear off pears for life. Even if you did, many other fruits and vegetablesOpens in a new tab contain formaldehyde too, but the amounts are so small that they don’t qualify as a “poison” to our bodies.

On the flip side, water is so essential to our health that humans can survive only about three days without it. But too much of anything can be harmful, including H2O. Drinking six liters in three hours has killed at least one personOpens in a new tab from water intoxication.

The Ames Test illustrates this well. Dr. Bruce Ames developed a testOpens in a new tab so sensitive it could detect mutagenic activity — mutations that could potentially lead to cancer — in everyday substances like coffee. It was a major scientific advancement. But when the media and public saw those results, many people interpreted them as “coffee causes cancer.”

They lacked the context to understand that the world is full of substances that can cause mutations in cells at high doses, but in the tiny amounts we typically encounter them, they are unlikely to cause harm.

Ames spent much of his later career emphasizing this exact point: Detecting something potentially dangerous does not mean detecting actual danger.

The bottom line: Whether a substance is dangerous does not depend only on what it is. It also depends on how much you consume.

Why route of exposure matters

There are multiple ways substances can enter our bodies: ingesting them through our mouths, inhaling them through our noses, absorbing them through skin contact, or injecting them directly into our bodies.

And the way our bodies interact with these substances can depend on how they enter our body.

We can consume some substances in food that might be dangerous if we encountered them another way. But if we eat them, our digestive system, with its strong acids and highly efficient ability to pull nutrients from our food, can limit absorption of them (depending on the exact substance and the dose) without them causing too much harm.

For example, coffee. It’s a great way to get a morning dose of caffeine, but hooking yourself up to an IV of coffee could be lethalOpens in a new tab. Route of exposure matters.

And let’s recall our pear example. Pears contain formaldehyde, a known carcinogenOpens in a new tab. But the amount of it in pears is far too small to be a concern. Formaldehyde’s health effects depend on both how we encounter it and how much — formaldehyde is most concerning when inhaled in large amounts, not eaten in trace amounts.

Similarly, some shampoos contain formaldehydeOpens in a new tab that can cause irritation for some people with sensitive skin, but it certainly does not increase their risk of cancer.

Why bioavailability is key

Just because you consume something doesn’t mean your body absorbs it. That depends on a substance’s bioavailability, the proportion of a substance that actually enters our body’s blood circulation.

Route of exposure can affect bioavailability too. Some medications, such as insulin for people with diabetes or pitocin to induce labor during pregnancy, are given through an injection or IV, for instance, because the body cannot access enough of the drug’s active ingredients if the person takes it orally.

For any substance to affect our health — positively or negatively — the body usually has to absorb it or inhale it directly into your lungsOpens in a new tab. Sometimes even seemingly small differences in a chemical’s make-up can affect its half-life (aka, the time it takes for half of it to be eliminated from the body).

Two different kinds of mercury compounds serve as good examples of this:

That means ethylmercury clears from our bodies much faster than methylmercury — though their differing toxicity reflects their distinct chemical forms too, not just how fast each clears.

Bioavailability also depends on how substances we consume interact with other chemicals. One reason people need vitamin D is because the vitamin helps the body absorb enough calciumOpens in a new tab. Without enough vitamin D, you only absorb 10%–15% of calcium, but with enough vitamin D on board, you’ll absorb 30%–40%.

The flipside is also true: Some substances can prevent absorption. We noted above that mercury from fish has a pretty long half-life, potentially sticking around in our bodies for months. But you can reduce how much mercury your body absorbs by getting enough seleniumOpens in a new tab, as it binds to mercuryOpens in a new tab and creates a compound that your body filters out as waste without absorbing it.

Fish can be a key part of a healthy diet, offering essential nutrients like omega-3s that reduce inflammationOpens in a new tab and support heart and brain healthOpens in a new tab. Avoiding fish entirely because of mercury concerns means losing those benefits, and that’s a poor trade-off for your health.

The smart approach: Eat fish with a high selenium contentOpens in a new tab, such as yellowfin tuna, sardines, shrimp, and salmon. Selenium may help offset some of the mercuryOpens in a new tab these fish contain, so you can get the omega-3s while lowering your risk.

Understanding the actual risks versus the proven benefits gives you the knowledge to make decisions accordingly.

How your body naturally detoxes heavy metals

Finally, our bodies are not defenseless. Our digestive systems are remarkably sophisticated machines, designed to pull nutrients from our diet while filtering out toxins and waste.

The liver and kidneys partially eliminate what we don’t need — including a sizable portion of the trace amounts of heavy metals we naturally consume every day.

Why individual sensitivity matters

Everyone’s body handles heavy metals differentlyOpens in a new tab. For example, the half-life of methylmercury can vary by weeksOpens in a new tab or more between individuals.

And some people are also more vulnerable to risks from heavy metals. Age, genetics, sex, nutrition, health status, and exposure history can all change how our bodies react. Children’s digestive systems absorb more leadOpens in a new tab, and their bodies aren’t developed enough to block lead from reaching the brain or to detox efficiently.

How to Make Food Decisions Without Fear

If we allow fear of heavy metals and other toxic substances in foods to drive our dietary decisions, then we run the risk of missing out on key nutrients that support long-term metabolic health.

The alternative to fear-based decision-making is looking at the bigger picture, weighing the actual risks against the proven benefits, and making decisions that maximize our health.

In doing so, we also have to accept the trade-offs. We can’t eat “perfectly,” but we can eat healthfully by making practical nutrition decisions that minimize — not eliminate — trace exposures and ensure we get the essential nutrients we need to live and perform optimally.

Approaching our health decisions with pragmatism instead of perfectionism can help reduce anxiety and the cognitive drain of obsessing about every potential threat (and losing the plot along the way). Constant food fear has real costs: It harms our mental healthOpens in a new tab, limits dietary variety, and can create the very nutritional deficienciesOpens in a new tab we’re trying to avoid.

5 questions to ask before worrying about food headlines or claims

When you come across a claim about a food containing a certain toxic compound, stop and consider several questions:

  • How much of a dose am I actually consuming?
  • Has that dose been shown to cause harm by public health authorities who have evaluated the consensus of research in this area? Check the FDA (for food and drinks), EPA (for environmental contaminants), or WHO (for international standards) to find out what regulatory limits exist and whether your exposure exceeds them.
  • Have scientists shown that consuming this substance is actually harmful compared to inhaling or injecting it?
  • How much of this substance will your body actually absorb? How long is its half-life? Are there other compounds you’re eating that increase or decrease how much of it your body absorbs?
  • Is this a substance your body’s natural detox functions are already well-equipped to filter out?

You may not be able to answer all of these questions, but simply asking them can help slow down the panic that might overwhelm you when you first read an alarming claim about heavy metals or other toxic substances in foods.

The Bottom Line: Balancing Caution and Context When Making Food Choices

We don’t want to downplay the fact that some foods can contain harmful chemicals that we need scientists and public health authorities to work together to identify and regulate. But current evidence indicates that the levels of heavy metals typically found in foods are low and unlikely to hurt most people.

It’s still important to read lists of ingredients and pay attention to nutrition labels. But it’s also important to focus on the “big rocks” that will help move the needle on your metabolic health: eating adequate protein, choosing whole foods over ultra-processed ones, staying properly hydrated, getting quality sleep, managing stress. These fundamentals matter far more than obsessing over parts-per-billion measurements of trace metals in otherwise nutritious foods.

Understanding the impact of dose, route of exposure, bioavailability, and your body’s natural detoxification of the foods you consume can help you make better sense of claims you see about heavy metals in our food.

NextPart 03 · Understanding heavy metal regulations like Prop 65

Part 03

Understanding heavy metal regulations like Prop 65

Understanding heavy metal regulations like Prop 65

It’s on your coffee, your spinach, and the parking garage wall. That warning means a lot less than you think.

In California, Proposition 65Opens in a new tab warnings are nearly impossible to avoid. They appear in parking garages, on coffee cups, and across grocery aisles from protein powders to even organic spinach. If you steered clear of every product bearing the label, you’d be severely limiting your diet. But Proposition 65 was designed to inform consumers about potential exposures to certain chemicals, not to declare that a product is unsafe.

So what does that warning actually mean?

Earlier in this series, we explored why trace metals in today’s foods are far lower than in the past and introduced the principles that distinguish toxic exposure from harmless trace presence.

Now we’ll break down where the heavy metal regulations — specifically Proposition 65 — come from, how safety limits are set, and why even safe foods sometimes carry warnings.

What Is Proposition 65? A Brief History

In the early 1980s, California found that over 100 Silicon Valley wellsOpens in a new tab were contaminated with toxic chemicals from semiconductor manufacturing.

Frustrated that state agencies had failed to adequately address the problem, California residents voted on and passed the Safe Drinking Water and Toxic Enforcement Act of 1986Opens in a new tab.

This law mandates the state to maintain a list of chemicalsOpens in a new tab “known to cause cancer, birth defects or other reproductive harm” and requires that businesses either:

  • Prove that exposure to these chemicals is below state-defined “safe harbor” levels, OR
  • Provide a “clear and reasonable warning”

The Safe Drinking Water and Toxic Enforcement Act of 1986 — often referred to as Prop 65 — was aimed at preventing contamination of drinking water and protecting consumers from significant chemical exposures.

But as the list of regulated substances expanded from a few dozen to around 900 chemicals, the warning requirements grew. With advances in testing technology capable of detecting substances at parts per billion, everyday products began to qualifyOpens in a new tab — including those containing trace amounts of naturally-occurring elements like lead or cadmium.

Fast-forward to today and what began as an environmental safeguard is one of the most misunderstood consumer warnings in the country.

How Are Prop 65 Safety Limits Calculated?

A Prop 65 warning doesn’t mean a product is dangerous. It means the product exceeded California’s extremely cautious threshold. But what is California’s threshold?

A warning is required when exposure to a listed chemical exceeds the state’s “safe harbor” level — limits that already include large safety marginsOpens in a new tab. For reproductive toxicants, that level sits 1,000 times below the no observable effect levelOpens in a new tab identified in toxicology studies. For cancer risk, a warning must be given when exposure to a chemical could cause at least one case of cancer for every 100,000 people exposedOpens in a new tab.

These levels are set by California’s Office of Environmental Health Hazard AssessmentOpens in a new tab (OEHHA) in two steps:

Step 1: A scientific organization approved by OEHHA reviews toxicology data to determine the no observable effect levelOpens in a new tab (NOEL) for reproductive harms, the “maximum level of exposure at which a chemical has no observable reproductive effect” or no significant risk levelOpens in a new tab for cancer, “the level of exposure that would result in not more than one excess case of cancer in 100,000 individuals exposed to the chemical over a 70-year lifetime.”

Step 2: The NOEL number is then divided by additional safety factors to account for human variability and long-term exposure, resulting in limits intentionally far below any level expected to pose real-world risk.

Here’s what that looks like in practice:

So a product that exceeds California’s threshold may still be well within federal safety limits. The difference reflects California’s modeling assumptions and extra safety margins, not actual health hazards.

In other words, a Prop 65 warning doesn’t automatically mean danger.

Why a Prop 65 Warning Doesn’t Mean a Product Is Dangerous

An extra safety margin sounds like a good thing, but Prop 65’s thresholds are so far below any demonstrated risk that warnings now appear on everything from coffee to seafood to wooden furniture.

The result isn’t necessarily greater safety; it’s greater confusion.

Key takeaway

When everything carries a warning, the warning means nothing.

The key thing to remember is that a Prop 65 label is a legal disclosure, not a scientific statement of danger. It’s required when estimated exposure exceeds California’s safe harbor level, but companies may also apply it based on the presence of a listed chemical alone, without estimating exposure at all. Either way, the label doesn’t tell you a product is harmful.

In most foods, human exposure to harmful chemicals is far below levels that raise concern. Many whole foods naturally contain trace amounts of substances that appear on the Prop 65 list simply because of how they’re grown, processedOpens in a new tab, harvested, or cooked — from minerals absorbed in soil to compounds formed through heat.

CocoaOpens in a new tab, spinachOpens in a new tab, seaweedOpens in a new tab, and root vegetablesOpens in a new tab can all contain measurable levels of metals like lead or cadmium, even though they’re widely recognized as safe and nutrient-dense.

Ironically, a truly “toxin-free” diet would mean eliminating most fresh foods and eating mostly high-calorie and low-fiber ultra-processed products — the very foods driving today’s metabolic health crisisOpens in a new tab.

And the obsession with eliminating all exposure overlooks a basic biological principle: small amounts of stress can be beneficial. Known as hormetic stressOpens in a new tab, this concept reflects how low-level challenges can, in some cases, strengthen cellular defenses and build resilience to larger impacts over time. There hasn’t been much research on Prop 65 chemicals and hormetic stress in people, but preliminary evidenceOpens in a new tab suggests that exposure to low levels of some heavy metals can, for example, boost cells’ ability to protect themselves from various stressors.

Lead reference levels
Lead per serving
micrograms
Prop 65 · 1,000× safety buffer

Drag or tap + to zoom in and compare vegetables and LMNT against Prop 65’s 1,000× safety buffer.

Sources: OEHHA reproductive-toxicity values (Prop 65 MADL = NOEL ÷ 1,000) & FDA interim reference levels.

Why Are Prop 65 Warnings on Everything?

Today, the Prop 65 list includes about 900 chemicals. Because private individuals and law firms can file Prop 65 lawsuits and collect a portion of the civil penalties (aka, make a profit), the system unintentionally incentivizes over-warningOpens in a new tab. To avoid litigation, some companies may choose to label products even when exposure is negligible, especially since fines can reach up to $2,500 per violation per day.

As a result, consumers encounter warnings on many everyday items that are unlikely to pose a meaningful health risk, from vegetables and coffee cups to makeup and cookware. That’s why a Prop 65 label, on its own, shouldn’t be a deciding factor. Context and credible science matter far more than a blanket warning.

This challenge echoes one of toxicology’s most famous ironies. Dr. Bruce Ames — creator of the Ames TestOpens in a new tab, a breakthrough tool for detecting mutagenic compounds — watched as results from his own invention were taken out of context. The test (which is extraordinarily sensitive) flagged mutagenic activity in coffee. But instead of treating those findings as preliminary screens that require context and dose considerations, some people and headlines leapt to conclusions that coffee causes cancerOpens in a new tab.

Ames spent much of his later career explaining that detection isn’t danger. The world is full of compounds that can trigger a positive result in a lab test, but that doesn’t mean they pose a real-world risk at the amounts people actually encounter.

His message was simple: Don’t confuse the ability to detect a trace hazard with evidence that it can cause harm.

It’s the same misunderstanding that fuels Prop 65 over-warning today — a tendency to “major in the minors” by focusing on what we can detect instead of what meaningfully impacts health.

When every trace becomes a trigger for alarm, genuine risks fade into the background. The result isn’t greater safety, but greater confusion about what deserves your time, money, and energy in the pursuit of health.

How to Tell Which Food Safety Warnings Matter

Next time you are at the grocery store, ask yourself three simple questions:

  • Is it sold nationwide? If you can buy it in stores across the U.S., it probably meets federal safety standards. The Prop 65 warning reflects California’s uniquely strict limits — as an overly-cautious warning — not a safety issue.
  • Does every brand have a warning? Look at the shelf. If ALL the dark chocolate bars, ALL the canned tuna, or ALL the coffee has the warning, it’s probably about unavoidable trace amounts, not unsafe products.
  • Is it a whole food from nature? Seafood, leafy greens, root vegetables, nutsOpens in a new tab, and chocolate contain naturally-occurring trace minerals from soil and water. The warning doesn’t mean they’re unsafe to eat or should be avoided.

A simple rule of thumb: If it’s a normal grocery store item that’s been sold for years, it’s probably safe despite the warning.

There are a couple of events that would warrant attention.

Product recalls or contamination events: This refers to situations where a government agency (FDA, USDA, or California regulators) identifies a real safety problem like Salmonella in peanut butter or lead in candy. These are actionable warnings that indicate an actual health risk. For updates and notices on specific recalls or events you can check:

Industrial exposure (e.g., water, occupational settings): This points to scenarios where people might encounter high levels of a chemical in the course of work or from environmental contamination like lead from a factory or contaminated drinking water. You can refer to websites and tools like:

But foods or products with Prop 65 labels don’t automatically mean you need to avoid them. Instead, focus on overall diet quality and nutrient density. Prioritize variety and balance, not trace detection. And remember that in most cases your body can naturally detoxify a large portion of the heavy metals you’re exposed to.

The takeaway isn’t to ignore safety, but to interpret warnings wisely. Understanding the difference between real risk and regulatory noise lets you make informed, confident choices.

NextPart 04 · How to read a toxicology report

Part 04

How to read a toxicology report

How to read a toxicology report

‘Billion’ sounds huge, so it sounds scary. Three steps of simple math cut it down to size.

Knowing how to read a toxicology report — multiply parts per billion by the serving size in grams, and divide by 1,000 to find micrograms per serving — is one of the most empowering skills you can develop as a health-conscious consumer. If you’ve been following our Toxicology in Context series, you already understand that detection doesn’t equal danger. Dose, exposure, and bioavailability are what matter.

If “any amount” of a heavy metal was dangerous for you, you couldn’t eat carrots, spinach, apples, or seaweed — since virtually all plants naturally absorb trace elements from soil and water. The issue isn’t whether you can detect a metal in your food but whether there’s enough of it to affect your health.

So how do you figure that out? By doing the math.

What if you could look at any lab report and understand — mathematically and contextually — what it means for your health? Not guess, not worry — actually know.

The math is simpler than you think, and once you see how to convert parts per billion into real serving sizes, those big numbers will start making a lot more sense.

Let’s walk through it together.

What Does Parts Per Billion Mean?

Parts per billion (ppb) is a measurement of concentration. It’s a way to describe how much of one thing is present in a larger amount. In solid foods, ppb is the number of micrograms per kilogram. (Don’t worry, we’ll break this down further.)

The number itself — billion — carries psychological weight. Our brains evolved to assess threats in our immediate environment, not to intuitively or automatically grasp quantities at this kind of scale.

So what does one part per billion represent?

Consider an Olympic-sized swimming pool. One ppb is equivalent to a single drop of water in that pool.

Said another way, a single ppb is incredibly small. When a headline or report states “27 parts per billion of lead,” that means 27 micrograms of lead in every kilogram (2.2 pounds) of food. Picture those 27 grains of sand distributed throughout 2.2 pounds. That’s the concentration we’re talking about.

Following so far? Let’s double tap on defining a kilogram.

A kilogram (2.2 pounds) is about the weight of a small pineapple — far more than you’d usually eat in a single serving. So that 27 ppb measurement isn’t what’s found in your cup or on your plate; it represents what you’d consume if you ate roughly 7–33 servings of most foods.

Lab reports list concentrations per kilogram for scientific accuracy, but news stories rarely translate that into actual serving sizes. The typical person doesn’t convert kilogram measurements to actual serving sizes but you can once you know how.

Key takeaway

Per kilogram is not per plate.

Let’s put those conversions into action with some real world examples.

How to Convert ppb to Serving Sizes (in 3 Steps)

There’s a simple 3-step formula to convert ppb into the actual amount in a single serving:

1. Find the ppb number

2. Multiply it by the serving size in grams

3. Divide by 1,000 to find out the micrograms per serving

That’s it. Now you know what’s in a portion.

For example, Girl Scout cookies made headlinesOpens in a new tab not long ago over claims about heavy metals — lead, arsenic, cadmium, aluminum and mercury. The claims originated from a reportOpens in a new tab on a website that promises to reveal the “hidden dangers” in our food.

The report labeled Peanut Butter Patties as one of the “most contaminated” cookies, citing 42.5 ppb of lead. That sounds like a lot, but that’s per kilogram (2.2 pounds) and there isn’t even a full kilogram of cookies in one box.

Let’s calculate what is in a single serving of Peanut Butter Patties:

Step 1: Find the parts per billion number. The amount given in the report is 42.5 ppb.

Step 2: Multiply the ppb number by the serving size in grams. The nutrition label shows a serving is two cookies (25 grams).

So 42.5 x 25 = 1,062.5

Step 3: Divide by 1,000 to get micrograms per serving

1,062.5 ÷ 1,000 = 1.06 micrograms per serving.

Now remember how infinitesimal one microgram is — comparable to a grain of sand in a mini fridge. That’s roughly what you’d consume (not absorb) if you ate two Peanut Butter Patties.

Next step: Let’s compare this to what’s naturally present in other foods.

How Much Lead Is Natural in Vegetables?

A 2018 peer-reviewed studyOpens in a new tab measured heavy metal levels in the five most consumed vegetables in the U.S: potatoes, carrots, onions, lettuce, and tomatoes.

The researchers collected both organic and conventional samples of each one from four grocery stores in a Florida college town.

Next, they tested the samples for nine metals: arsenic, cadmium, lead, chromium, barium, cobalt, nickel, copper, and zinc.

To keep things simple, we’re just going to focus on what they found for lead since that’s what we looked at in the Peanut Butter Patties.

Here are the results for average ppb of lead in the five vegetables Americans eat the most:

Vegetable Organic sample (microgram/kilogram) Conventional sample (microgram/kilogram)
Tomato 5.0 ppb 7.7 ppb
Lettuce 12.0 ppb 25.3 ppb
Onion 3.0 ppb 19.0 ppb
Carrot 7.2 ppb 22.4 ppb
Potato 32.6 ppb 16.5 ppb

Let’s walk through our calculation steps again — this time, for organic potatoes.

Step 1: Find the parts per billion number for organic potatoes. It’s 32.6.

Step 2: Multiply it by the serving size in grams. The FDA considers one servingOpens in a new tab to be one medium-sized potato, which is about 148 grams.

So 32.6 x 148 = 4,824.8.

Step 3: Divide by 1,000 to find out the micrograms per serving.

4,824.8 ÷ 1,000 = 4.82 micrograms per serving.

That’s 4.5 times as much lead as there was in one serving of Peanut Butter Patties! And that’s for an organic potato too. The lead amounts in the other vegetables were higher in the conventional samples than in the organic ones, but it’s interesting that it happens to be higher in organic potatoes than in conventional potatoes.

What about the other vegetables? We did the math for you, using those FDA serving sizesOpens in a new tab, so you can see how much lead is in other common organic vegetables:

Organic Vegetables PPB (mcg/kg) Standard serving size Amount per standard serving
Tomato 5.0 148 g 0.74 mcg
Lettuce 12.0 85 g 1.02 mcg
Onion 3.0 148 g 0.44 mcg
Carrot 7.2 78 g 0.56 mcg
Potato 32.6 148 g 4.82 mcg

And here are the calculations for conventional samples of the same vegetables.

Conventional Vegetables PPB (mcg/kg) Standard serving size Amount per standard serving
Tomato 7.7 148 g 1.14 mcg
Lettuce 25.3 85 g 2.15 mcg
Onion 19.0 148 g 2.81 mcg
Carrot 22.4 78 g 1.75 mcg
Potato 16.5 148 g 2.44 mcg

Even the highest levels here would require someone to eat multiple large servings at once to come close to the safety thresholds set by international health organizations. These trace amounts are exactly what scientists expect to find in food grown in soil.

The bottom line: The trace amounts typically found in these vegetables are generally not considered a health concern based on current evidence.

So let’s talk about LMNT…

Now that you know what’s typical in food, let’s look at how much lead is in LMNT. An influencer tested LMNT for leadOpens in a new tab and found that it contained 27 ppb — results that align with our own testing. (We test every batch of our product for heavy metals as part of our quality controlOpens in a new tab.)

Step 1: Find the parts per billion number. The amount is 27 ppb.

Step 2: Multiply the ppb number by the serving size in grams. One stick pack of Raw Unflavored LMNT is 3.5 grams.

So 27 x 3.5 = 94.5

Step 3: Divide by 1,000 to find out the micrograms per serving.

94.5 ÷ 1,000 = 0.095 micrograms per serving.

To put that in perspective: a single serving of the vegetables above contains roughly 6 to 51 times more lead than an LMNT stick pack. And a stick pack itself sits more than five times below California’s Prop 65 threshold — already one of the strictest limits.

Just like the per-serving levels of lead in vegetables aren’t considered dangerous, neither is the much smaller amount of lead in LMNT. Instead, we know that vegetables are vital to a healthy diet — as are sodium and other electrolytes.

Why Your Body Doesn’t Absorb Every Trace Metal You Eat

Your body is smarter than you think. It doesn’t absorb everything you eat. Lots of factors affect how much of something you consume gets absorbed by your body. This is called bioavailability, and it is affected by:

NextPart 05 · Does your body absorb heavy metals? Bioavailability explained

Part 05

Does your body absorb heavy metals? Bioavailability explained

Does your body absorb heavy metals? Bioavailability explained

You are what you eat? Not quite. You’re what you absorb, and your body takes in as little as 3% of the lead in your food.

If you believe TikTok, everything in your pantry is trying to poison you. One week it’s Girl Scout cookiesOpens in a new tab or protein powdersOpens in a new tab laced with lead. The next, it’s farm-fresh veggies riddled with arsenic. The implication: If it’s in your food, it’s in your body, and that’s bad news.

But it’s not that simple, or that scary. Many foods contain trace heavy metals because these elements occur naturally in soil and water and make their way through the food chain into produce and meat. But your gastrointestinal tract isn’t a pipeline straight to your bloodstream. It’s a selective filter that blocks, binds, and eliminates heavy metals to reduce the amount entering your bloodstream and the risk of harm to your health. Only a fraction of the heavy metals you eat are absorbed; most pass right through your system.

This concept — that not everything you eat is absorbed — is called bioavailability, and understanding it will help you separate real toxicology from fearmongering.

Key takeaway

Consuming it isn’t absorbing it.

Does Your Body Absorb All the Heavy Metals You Eat?

No, your body only absorbs a small fraction of the heavy metals you consume. This fraction — known as a food’s bioavailability — depends on a long list of factors including what else you eat, your nutrient status, gut health, age, and more.

Keep in mind, many essential minerals you actually need for life, like iron, zinc, and copper are heavy metals in the chemical senseOpens in a new tab.

The ones worth worrying about are the non-essential metals, like lead, cadmium, mercury, and arsenic. These serve no useful purpose in the body, and at high enough levels, they can cause harm. But here’s the part that usually gets lost in translation: dose and absorption matter. Most vitamins, minerals, and metals can be toxic at certain levels; it’s the exposure and bioavailability that make the difference.

Trace amounts of non-essential heavy metals show up naturally in food, but your body only absorbs a small fraction of them. Here’s what the research suggests about approximately how much is absorbed in adults in typical dietary situations:

Some of those percentages might look alarming, but keep this in mind: These are percentages of an already small amount. Research shows that the heavy metal content in a serving of many wholeOpens in a new tab and packaged foodsOpens in a new tab falls well under federal and international safety limits.

To put it in perspective, let’s look at the amount of lead in a serving of four common foods, along with how much your body actually absorbs, based on a 3–10% absorption rate.

As you review this table, keep in mind that the FDA recommends total daily lead intake from food stays under 8.8 mcg for women of childbearing ageOpens in a new tab — its most protective limit — and under 12.5 mcg for the general adult populationOpens in a new tab.

Food (1 serving) Lead present (mcg) Estimated amount absorbed
LMNT Raw Unflavored (1 stick pack) 0.1 mcg 0.0003–0.001 mcg
Peanut Butter Girl Scout Cookies (2) 1.06 mcg 0.032–0.106 mcg
Potato (1 medium, conventionally grown) 3 mcg 0.09–0.3 mcg
Carrots (½ c, organic) 0.92 mcg 0.028–0.092 mcg

Even at the high end, these absorbed quantities are so microscopic they’re not even visible to the human eye. A single grain of salt weighs about 60 mcgOpens in a new tab — that’s about 566 times heavier than the amount of lead absorbed from any of the foods above.

What’s more, a portionOpens in a new tab of the small amount your body absorbs is processed and excreted through stool and urine. For example, most of the arsenicOpens in a new tab your body absorbs is converted into a less harmful form by the liver and 70–80% is cleared out within a week.

How Food Protects You From Heavy Metal Absorption

Your body doesn’t passively soak up whatever you eat. Many whole foods contain nutrients and compounds that bind, block, or escort heavy metals out of your system.

Selenium: Counteracts mercury

Selenium is a mineral that binds strongly toOpens in a new tab mercury. When these two nutrients are ingested together, less toxic mercury-selenium complexesOpens in a new tab are formedOpens in a new tab, which are harder to absorb and easier to eliminate.

Selenium may also play a role in demethylationOpens in a new tab, the process that converts methylmercury (the more absorbable form) into inorganic mercury, which is largely excreted. This is an active area of research, with much of the evidence so far coming from experimental studies.

And it supports a healthy gut barrierOpens in a new tab, which prevents metals from “leaking” into circulation.

While fish is often flagged for containing high levels of mercury, headlines don’t mention that many speciesOpens in a new tab also contain seleniumOpens in a new tab. When selenium levels exceed mercury levels (the case in nearly all commonly eaten fishOpens in a new tab), selenium may help reduce mercury toxicity by forming stable complexes.

Bottom line: For most people, eating two to three 4-ounce servingsOpens in a new tab of salmon, sardines, or trout each week keeps mercury exposure within safe limits while providing omega-3 fats, protein, and other essential vitamins and minerals.

Calcium, iron, and zinc: Block heavy metal absorption

Heavy metals and essential minerals compete for the same nutrient transport proteins in your gut. When you eat nutrient-dense meals, more minerals occupy these transporters, leaving fewer available for heavy metals, effectively blocking their absorption.

Fiber and phytochemicals: Bind and block heavy metals

Compounds in plant foods, including dietary fiberOpens in a new tab, polyphenols and other phytochemical compounds reduce absorption of heavy metals. This may be because they bind to heavy metals in the gut, forming complexes that are too large to cross the intestinal wall and unable to use metal transporters.

The result: Heavy metals like mercury, Opens in a new tabcadmiumOpens in a new tab, leadOpens in a new tab, and arsenicOpens in a new tab are excreted instead of absorbed. Phytochemical compounds with heavy metal-reducing properties include:

FiberOpens in a new tab and phytochemicalsOpens in a new tab also support a diverse, resilient gut microbiome and strengthen the intestinal barrier, both of which may further reduce heavy metal absorptionOpens in a new tab.

Probiotics: Support a healthy gut barrier

ResearchOpens in a new tab suggests consuming certain probiotics strains (via yogurt or supplements) may reduce blood levels of heavy metals in people with known exposure. The likely reason: reduced absorptionOpens in a new tab in the gut.

Here’s what might be causing that:

Although early findings are promising, much of this evidence comes from animal and lab studies, with only limited human research so far — more is needed to confirm these effects.

The bottom line here: Foods often flagged for containing heavy metals also contain nutrients that prevent their absorption. Testing reports measure total content but don’t reflect these protective interactions, missing the complete biological picture.

Why Do Some People Absorb More Heavy Metals Than Others?

Two people can eat the same meal and absorb very different amounts of heavy metals. That variability comes down to individual factors like nutrient status, life stage, and gut health.

Nutrient deficiencies

Low mineral status opens the door to higher metal absorption. Iron, zinc, and calciumOpens in a new tab deficiencies are linked to higher absorption of heavy metals like leadOpens in a new tab and cadmiumOpens in a new tab. Animal studiesOpens in a new tab have found that mice on a calcium-deficient diet eliminated 40% less lead than mice who got enough calcium.

Here’s why: When you’re low on these nutrients, it makes it easier for heavy metals to attach to the nutrient transporters in the gut and enter your circulation. Mineral deficiencies often trigger the body to create more of these transportersOpens in a new tab, giving heavy metals more “doors” to slip through and less competition to get through them.

Life stage

Children can absorb 40–50%Opens in a new tab of the lead they ingest. That’s about 4–5 times as much as adults, and they’re more likely to be on the high end if they have iron and calciumOpens in a new tab deficiencies.

Although research is lacking, pregnant women may also absorb more heavy metalsOpens in a new tab. That’s because as nutrient demands rise, many pregnant women experience nutrient deficienciesOpens in a new tab that can increase heavy metal absorptionOpens in a new tab.

ResearchOpens in a new tab in rats suggests that pregnancy may also increase the numbers of nutrient transporters, which can let more heavy metals into the body.

Gut microbiome and barrier function

Your intestinal lining is meant to be selectively permeable, allowing for the regulated uptake of vitamins, minerals, and other nutrients into circulation, while keeping harmful compounds out — or at least reducing their absorption.

AlcoholOpens in a new tab, low fiber intakeOpens in a new tab and high sugar consumptionOpens in a new tab disrupt the balance of microbes, leading to changes that make the gut barrier “leaky,” or less discerning about what (or how much) gets through. When that happens, heavy metals may have an easier route into circulationOpens in a new tab.

Gut microbiome disruption can also blunt demethylationOpens in a new tab of a highly toxic form of mercury, a reaction that makes mercury less bioavailable and less toxic.

What Bioavailability Means for Your Daily Food Choices

Most foods contain trace heavy metals, but most healthy adult bodies are generally well-equipped to handle those miniscule exposures, especially when you’re properly nourished. So it’s best not to fixate on whether a specific food contains metals.

Instead ask: “Am I eating in a way that minimizes their bioavailability?” Here’s what that looks like in practice:

  • Focus on overall diet quality, not trace-level contamination. Build meals around whole and minimally processed vegetables, fruits, nuts, seeds, legumes, healthy fats like olive oil, and high-quality dairy, fish, and meats. These foods supply the minerals that block metal absorption and the fiber that helps remove what gets through.
  • Meet your mineral needs. Regularly eat foods rich in calciumOpens in a new tab (e.g. dairy, sardines and salmon with bones, dark greens), ironOpens in a new tab (e.g. beef, beans, lentils, spinach), zincOpens in a new tab (e.g. fish, oysters, meat, pumpkin seeds), and seleniumOpens in a new tab (e.g. Brazil nuts, sardines, cottage cheese, eggs). Getting enough of these minerals ensures that transport proteins in the gut move nutrients into circulation instead of heavy metals.
  • Maintain a healthy gut. A healthy microbiome supports detoxification and gut barrier integrity. Prioritize fiber, probiotic-rich fermented foods, and colorful plant foods containing phytochemicals. Limit alcohol and sugar and take steps to curb stress.

Trace heavy metals are everywhere, but your body has systems in place to deal with them. So don’t major in the minors. Stay nourished, keep your gut healthy, and you’ll have already solved most of the problem.

NextPart 06 · Mechanisms of detoxification: How the body clears heavy metals

Part 06

Mechanisms of detoxification: How the body clears heavy metals

Mechanisms of detoxification: How the body clears heavy metals

There’s no cleanse to buy and no protocol to follow. Your liver, kidneys, and gut clear these metals every single day, for free.

Right now — with zero effort on your part — your body is clearing out the trace amounts of heavy metals that you inevitably consume through food and water.

Your kidneys filter about 50 gallons of bloodOpens in a new tab each day, eliminating potentially harmful substances. Your liver helps bind and package heavy metals and other compounds for excretion. Your gut — and the beneficial bacteria living there — help block, bind, and carry out trace metals and other compounds your body doesn’t need.

These and other detoxification processes happen automatically, 24/7, without any conscious thought on your part. It’s just your body, doing what it evolved to do.

Key takeaway

You’re detoxing right now. No protocol required.

Understanding how these systems work makes it a lot easier to assess whether or not you should be concerned about heavy metals.

How Your Body Naturally Removes Heavy Metals

Small amounts of heavy metals are naturally present in the soil and waterOpens in a new tab, and therefore, our food but our bodies evolved to deal with them, long before “detox protocols” were a thing.

Heavy metalsOpens in a new tab fall into two buckets:

  • Essential minerals: These are the ones your body needs to operate, like iron, zinc, and copper.
  • Non-essential metals: Metals like lead, cadmium, mercury, and arsenic that serve no nutritional or biochemical purpose in the body.

Both can be harmful at excessively high doses — for example, what you might encounter if you live somewhere that drinking water is delivered via lead pipes. But trace amounts — the kind you get through everyday exposures through food and water — aren’t inherently dangerous.

A significant percentageOpens in a new tab of the heavy metals you ingest are never absorbed by your body. Of the fraction that is absorbed, your liver, kidneys, and intestines bind, transport, and excrete them before they can ever do damage.

Heavy metal intake vs accumulation vs actual health risk

If you’ve heard “once metals enter your body, you’re stuck with them forever,” I’m here to tell you: That’s not how biology works.

For most folks, the amount of heavy metals you retain from normal food exposure is negligible, and well within what the body can clear.

Take lead, for example:

  • Only 3–10%Opens in a new tab of the lead present in food is absorbed into your bloodstream.
  • Of that amount, 50–60%Opens in a new tab is excreted from the body within weeks. An additional 25% is removed over time. (But don’t worry — you don’t keep a permanent 25% stash of lead in your body. Most of it is clearedOpens in a new tab, and the small amount that sticks around in bone stays far below anything harmful.)
  • Only about 1% of the lead youOpens in a new tab ingest from food is retained by the body — and those exposures are already far below regulatory limits for most packaged and whole foodsOpens in a new tab. If our daily intake of heavy metals truly overwhelmed our detox capacity for them, blood levels would steadily climb throughout life. The numbers show they don’t. The average blood lead level in U.S. adults is around 0.855 µg/dLOpens in a new tab, far below levels that typically prompt clinical concern in adults.

What’s more, a 2023 reportOpens in a new tab found that blood levels of lead, mercury, and cadmium have been steadily declining among Americans. This is thanks to a variety of public health measures like banning leaded gas, campaigns to reduce smoking, and lead paint remediation.

There are situations where our bodies’ detoxification capacity can be exceeded — but they look nothing like normal food exposure.

Chronic high-dose contact that can push metals into rangesOpens in a new tab that require medical treatmentOpens in a new tab largely comes from:

That’s a different universe from the trace amounts naturally present in everyday foods.

Your Body’s Natural Detox System and How It Handles Heavy Metals

Your body is a lean, clean, heavy-metal detoxifying machine. Here are the systems that bind, transform, and eliminate heavy metals:

Liver: Processing and Packaging

When you absorb trace amounts of heavy metals, they travel to the liver, where they’re bound, neutralized, and prepped for elimination.

Once the liver is done with them, heavy metal byproducts are released into bile for elimination with stool; the rest moves into the bloodstream for eventual filtration and removal by the kidneys.

Kidneys: Filtration and Elimination

The kidneys filter 50 gallons of blood per day, helping eliminate waste products via urine — the primary elimination route for leadOpens in a new tab, arsenicOpens in a new tab, and cadmiumOpens in a new tab.

What isn’t peed out gets reabsorbed into your bloodstream, simply because the kidneys aren’t great at telling the difference between the essential minerals your body needs and the non-essential heavy metals it doesn’t.

Making sure you don’t have any nutritional deficiencies may help limit reabsorption. For example, research in mice suggestsOpens in a new tab that being iron-deficient can cause the body to hold on to cadmium. (Worth acknowledging the relationship between nutrient deficiencies and heavy metal elimination in humans is more complex.)

Here’s the greatest irony: avoiding nutrient-dense whole foods like seafood, legumes, spinach, kale, nuts, and seeds because they contain trace metals is exactly the kind of behavior that can create those deficiencies in the first place. There are no perfect solutions here — only trade-offs. A nutrient-dense diet is one of the best things you can do for your detox machinery, and this is where people get to make calm, confident, science-informed choices instead of fear-driven ones.

Intestinal System: Binding and Elimination

Many heavy metals have low bioavailability, meaning they pass through the gastrointestinal (GI) tract without being absorbed. Good gut health and eating nutrients that bind to heavy metals — fiberOpens in a new tab (raspberries, artichokes, broccoli, and sweet potatoes, legumes, nuts and seeds) and various phytochemicals (dark leafy greens, berries, beans, tea, dark chocolate, onions, garlic, carrots, tomatoes) — can reduce their absorption even further.

For the metals that are absorbed, the intestines still play a major role: Once heavy metal-laden bile is released from the liver, it’s carried out in stool via the large intestine, or reabsorbed into the bloodstream and shuttled to the kidneys for clean up.

The intestines are also home to beneficial probiotic bacteria that trap and eliminateOpens in a new tab heavy metals or transform themOpens in a new tab into less bioavailable forms, though more human research is needed.

Additional Pathways

Urine and stool are the main ways your body gets rid of heavy metals. Small amounts can also end up in hair, nails, and skin because whatever’s circulating in your bloodstream gets built into those tissues as they grow. Once they’re locked in, they tend to stay there — which is why hair and nail tests can reflect past exposures, though these don’t pose a risk. Other heavy metals are eliminated through sweat in small amounts.

All of these pathways contribute to your overall elimination capacity and run simultaneously, helping prevent significant heavy metal accumulation.

8 Ways to Support Your Body’s Heavy Metal Elimination

Your internal detox systems work best when the basics of health are covered. These strategies help your built-in detox machinery run the way it’s supposed to:

1: Get enough protein.

Your body needs amino acids from dietary protein to make glutathioneOpens in a new tab and metallothioneinOpens in a new tab, the main compounds that bind to and neutralize heavy metals. Both are rich in cysteine, an amino acid found in foodsOpens in a new tab like whey proteinOpens in a new tab, soy, meat, and fish.

2: Eat a micronutrient-rich diet.

Vitamins and minerals support multiple detox pathways:

3: Increase fiber and phytochemical intake.

Dietary fiberOpens in a new tab and phytochemicals in plant foods (e.g. proanthocyanidinsOpens in a new tab in berries, carotenoidsOpens in a new tab in spinach, quercetinOpens in a new tab in apples with skin) can bind and clear heavy metals in the gut, decreasing reabsorption into the blood. Many phytochemicals are also antioxidants, and some (such as sulforaphane in cruciferous vegetables) support metallothioneinOpens in a new tab and glutathioneOpens in a new tab production.

4: Ensure regular bowel movements.

When stool sits in the intestines too long, material excreted through bile, like metals, have more time to be reabsorbedOpens in a new tab. Adequate fiber, hydration, and physical activity keep things moving.

5: Stay well hydrated: When you’re dehydrated, blood flow to the kidneys drops, and detox efficiency takes a hit.Opens in a new tab

6: Get enough sleep.

Your body handles a lot of its cellular cleanup and repair processesOpens in a new tab while you snooze. Sleep deprivation is linked toOpens in a new tab increased markers of tissue damage and oxidative stress in the liver — a central hub for metal processing.

7: Avoid excess alcohol.

Drinking alcohol can injure the liverOpens in a new tab and compromise the organ’s ability to process and package metals for elimination.

8: Exercise!

Sweating can remove small amounts of heavy metals from the body, but how you sweat may matter. One small studyOpens in a new tab suggested exercise-induced sweating eliminated more metals than sauna use, though more research is needed. Either way, if you’re sweating, you should be salting with electrolytes.

Why Most People Handle Heavy Metal Exposure Well

Understanding how your body handles heavy metals reframes the entire conversation from “everything is toxic” to “your physiology is built for this.”

Across this series, you’ve seen the bigger picture:

  • We’ve dramatically reduced major exposures over the past few decades.
  • Trace amounts aren’t dangerous because dose matters.
  • Prop 65 warnings don’t reflect real-world risk.
  • Parts-per-billion numbers only make sense when viewed in context.
  • Most of what you ingest isn’t absorbed.

This final piece adds the last link: What does get absorbed is steadily cleared.

Put together, the full picture is straightforward: Most consumed metals aren’t absorbed, the small fraction that enters circulation is continuously eliminated, and basic health practices help these systems run well.

With this knowledge, you can sidestep the fear-based stuff and put your time into changes that genuinely matter for metabolic health — and help others separate facts from fear.

Part 07

Meet the team behind Toxicology in Context

  • James Murphy is a co-founder and the CEO of LMNT.

    He’s spent most of his career in the health space — focused on building brands providing dietary and lifestyle interventions to chronic inflammatory conditions. He’s also been an investor in dozens of brands such as Primal Kitchen, Thrive Market, and Levels Health. James has built 5 natural products brands in partnership with leading experts in health.

    James and the leadership team plan to steward LMNT for the long-term and believe in the power of business to make a positive impact on metabolic health.

    A Yale Humanities grad, James stays connected to his alma mater via entrepreneurship support and guest facilitating at the Yale School of Management. He lives in Bozeman, MT with his wife Campbell and daughter Ember.

  • Robb Wolf is a former research biochemist, two-time New York Times and Wall Street Journal bestselling author, and co-founder of LMNT. With a background in biochemistry, laboratory research, environmental toxicology, and risk assessment, Robb has spent decades studying how nutrition and environmental factors affect human health and performance.

    He is the NYT/WSJ bestselling author of The Paleo Solution and Wired to Eat and co-author of Sacred Cow. Over the course of his career, Robb has worked with athletes, military personnel, and first responders and provided nutrition and strength-and-conditioning education to organizations including NASA, Naval Special Warfare, the U.S. Marine Corps, and Canadian Light Infantry.

    Robb also co-founded the first and fourth CrossFit affiliate gym and co-hosts the Healthy Rebellion Radio podcast with his wife, Nicki. He lives with his family in Montana.

  • Sharon is the SVP of customer experience at LMNT. As one of the team’s OGs, she started working with LMNT co-founder and CEO James Murphy in 2017, collaborating on brands including Everyday Leadership with Yale School of Management’s Heidi Brooks before helping build LMNT from the ground up in 2018.

    Born in South Africa, Sharon earned her degree from the University of Cape Town before moving to South Korea to teach English. She later relocated to New York City where she completed a summer publishing course at Columbia University’s Graduate School of Journalism and worked in the literary department at ICM Partners.

    Sharon is based in Bozeman, Montana with her fiancé Caleb and their dogs Kaya and Bo. She enjoys hiking, trail running, and live music.

  • Ecler Ercole Jaqua, MD, MBA, DABOM, FAAFP, AGSF, FACLM, AAHIVS, is an associate professor of Family and Geriatric Medicine and associate program director of the Loma Linda University Family Medicine Residency.

    Dr. Jaqua is board-certified in Family Medicine, Geriatric Medicine, Lifestyle Medicine, and Obesity Medicine. She has received a Lifestyle Medicine Interventionist certification and is an HIV specialist. In addition to her clinical achievements, Dr. Jaqua holds a Master of Business Administration with a focus on strategic leadership, which complements her work in education and program development. She is committed to advancing resident education and providing holistic care for patients of all ages.

    Dr. Jaqua lives with her husband and daughter in Loma Linda, California and enjoys singing, hiking, playing volleyball, and walking her dogs. She speaks English, Portuguese, and Spanish.

  • Tyler Santora is a freelance journalist, editor, and fact-checker based in Colorado, specializing in health and science reporting. They have a master’s degree in science and health reporting from New York University and have written for publications including Scientific American, Science, Chemical & Engineering News, and WebMD. They have fact-checked for publications such as Popular Science, Audubon magazine, Sentient, and more. Previously, they were the Health Editor at Fatherly.

    In their free time, Tyler enjoys running, fostering dogs, and writing fiction.

Additional Contributors

  • Third-party Accredited Laboratories
  • FBI Forensic Scientist
  • PhD Lab Engineers
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